Ethics and Research Using Ionising Radiation

29 October 2019


Organised by IPEM's Diagnostic Radiology Special Interest Group

Ionising radiation is commonly used in many research studies and the Medical Physics Expert has a crucial role in ensuring these studies comply with the requirements of IRMER and the new Health Research Authority (HRA) Radiation Assurance procedures which are being rolled out. This educational workshop aims to provide delegates with the most up to date advice and guidance from HRA, ARSAC and other relevant bodies in order to facilitate IRMER compliance. The role of both the Lead and Local Medical Physics Expert and the Clinical Radiation Expert will be discussed and ‘common sense’ methods for assessment of research proposals will be presented. 

Other topics will include dosimetry for research purposes, setting dose constraints and communicating risk with the aim of providing standardised approaches to guide the MPE. Controversial issues, communication difficulties and application of professional judgement will also be discussed. In the light of upcoming requirements for MPE accreditation the workshop will also provide training for those who are new to MPE reviews of research applications as well as a session on Good Clinical Practice. Educational sessions including worked examples of lead HRA-style reviews and local IRMER reviews by experts in the field from various modalities will be included. 

The workshop will be especially beneficial for trainee MPEs completing a portfolio, experienced MPEs from all ionising radiation modalities as well as those seeking registration as an HRA reviewer.

Target audience
Diagnostic Radiology, Nuclear medicine and Radiotherapy Physicists
MPEs in training 
Experienced MPEs seeking registration as HRA reviewers
Radiographers with an interest in research
Research trial practitioners

Learning Outcomes
A detailed understanding of the IRMER requirements for research using ionising radiation and application of these requirements following the latest guidance from relevant bodies including HRA and ARSAC.
Knowledge and awareness of strategies for dosimetry in research including calculating doses, setting dose constraints and communicating risk. 

A draft programme is available here. 

Invited speakers 

Giles Morrison
Medical Imaging and Medical Physics, Sheffield Teaching Hospitals NHSFT
Giles Morrison has been Head of Radiology Physics in Sheffield for 16 years. As a member of the IPEM Diagnostic Radiology SIG (2002-05) Giles approached COREC, asking the question whether they were aware that IR(ME)R 2000 placed requirements on the approval of research studies involving. This rapidly lead to the inception of what became Pat B Section 3 of the IRAS application form. COREC set up an Ad Hoc Working Group on Radiation Protection, which transitioned to NRES and produced the 2008 Guidance ‘Approval for research involving ionising radiation’. More recently Giles became a Health Research Authority ‘Radiation Guardian’ working with a team of MPEs around the country to streamline the approval process for research involving Ionising Radiation. Throughout this period Giles has kept the DRSIG appraised of developments and will present the latest updates on the HRA approvals process and related guidance. Presently Giles is the HRA 4-Nations Radiation Assurance Working Party representative for England.’

 John Kotre
British Institute of Radiology  
 ‘John Kotre led the Northern Regional diagnostic radiology physics and radiation protection services based in Newcastle-upon-Tyne for many years, and more latterly held a similar position for the North West, based at the Christie, Manchester. Throughout his time running services he attempted to do a little science around the edges and has over one hundred refereed scientific publications to date. For eight years prior to retirement in March he held a post with the Clinical Research Facility, Newcastle-upon-Tyne Hospitals FT, acting as Medical Physics Expert for clinical research applications.’ 
 Nasreen Parkar
Public Health England
Nasreen is based at Public Health England working as a Senior Clinical Officer in Nuclear Medicine as part of the Medical Exposures Group. Nasreen completed training as a Clinical Scientist, specialising in Nuclear Medicine and Diagnostic Radiology at St Georges Hospital, London and The Royal Marsden, Sutton. Since 2014, Nasreen has been focusing further on Nuclear Medicine to provide independent advice on IR(ME)R and updated guidance to the community on patient safety. Nasreen is most known for her ongoing role as a member of the Secretariat and as a Scientific Advisor for the Administration of Radioactive Substances Advisory Committee (ARSAC).
Frederick Wilson GlaxoSmithKline 
Director, Imaging Physics, Clinical Imaging, GlaxoSmithKline, Stevenage, UK.
Fred Wilson is a Medical Physicist who has been working on the application of Medical Imaging and Physiological Measurements to drug development since 2008.  He worked initially for 4 years at Pfizer (Sandwich, UK) and then as an independent consultant before joining GlaxoSmithKline (Stevenage, UK) in July 2014.  Prior to joining the pharmaceutical industry he worked as a Medical Physicist in the NHS and in several other science-focussed R&D roles in other industries.
Fred’s current role at GSK focuses on the use of medical imaging techniques in early stage trials of putative therapies for respiratory indications.  He is also the author of the company-wide and internationally-applicable Standard Operating Procedure on ‘Exposure of Human Subjects to Ionising Radiation’ and the nominated ‘Domain Expert’ who advises the Chief Medical Officer and Global Safety Board on issues relating t o the use of ionising radiation in clinical trials.
Fred holds an MA and MSci in Natural Sciences from the University of Cambridge and an MSc in Medical Physics from the University of Exeter, and is a member of the Institute of Physics (IoP), Institute of Physics and Engineering in Medicine (IPEM), International Pharmaco-EEG Society (IPEG) and the European College of Neuropsychopharmacology (ECNP).
Elly Castellano
The Royal Marsden NHS Foundation Trust
Elly leads the diagnostic radiology physics group at The Royal Marsden. She was educated in physics and medical physics at the universities of Oxford, Surrey and London.  She trained at St Mary’s Hospital, London, in nuclear medicine, radiotherapy and diagnostic radiology physics, and thereafter specialised in the latter.  She is a registered clinical scientist, chartered scientist, chartered radiation protection professional and certificated radiation protection adviser.  She was a member of the Health Research Authority’s radiation guardians group. 


On-line registration is now open. For any queries, email the IPEM conference team or ring 01904 550598.  

Workshop registration fees (including refreshments and lunch):

 Category Full     
 IPEM member £310 
 IPEM member trainee £260
 IPEM member technologist £230 
 IPEM member student/retired/non-salaried £170
 Non-member £410

Please note there is a £20 discount on these prices if booked up to 6 weeks in advance.

Registration deadline: 15th October

This conference will take place at Bristol Marriott Hotel City Centre. Further details can be found on their website:

If you have any queries, please 
email the IPEM conference team or tel: 01904 550598. 


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